(CNN)Cystic fibrosis did not define Claire Wineland. She did.
No matter the obstacles placed in front of her, of which there were many, she refused to be pitied and was determined to live a life that mattered. She inspired countless people, invited — no, demanded — honest talk about illness and mortality, and brightened the worlds of those she touched with her smile, spunk and spirit.
On Sunday evening, after being taken off life support and using the newly transplanted lungs she received just one week earlier, Claire took her last breath. The cause of death was a massive stroke she suffered soon after the transplant surgery. She was 21.